Pharmacokinetics, metabolism and safety of deuterated L-DOPA (SD-1077)/carbidopa compared to L-DOPA/carbidopa following single oral dose administration in healthy subjects
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چکیده
منابع مشابه
The Pharmacokinetics of Rafoxanide following Single Dose Intravenous and Oral Administration in Goats
The study was conducted to determine the plasma concentrations and pharmacokinetic parameters of rafoxanide after a single intravenous (10 mg/kg) and oral (22.5 mg/kg) administrations in black Bengal female goats. Maximum (87.63 11.71 mg/mL) and minimum (1.8 0.24 mg/mL) plasma concentrations of rafoxanide were recorded at 0.08 and 12 h respectively after i.v. administration. The elimination h...
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The advent of chloroquine promising activity against the COVID-19 is novel and as such, it is imperative to thoroughly understand and determine the rate at which individual body systems handle the drug. Chloroquine a known antimalarial drug belongs to the chemical class of 4-aminoquinolines. The aim of the study was to analyze Chloroquine and its metabolite in biological fluids of healthy subje...
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ژورنال
عنوان ژورنال: British Journal of Clinical Pharmacology
سال: 2018
ISSN: 0306-5251
DOI: 10.1111/bcp.13702